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Gleevec is a really wonderful medication that saves lives and helps people maintain clear mind. I'v been on it for more than seven years now and I've had no side effects with it. You just have to be careful when taking the medication together with other strong drugs. For example I had to stop taking Interferon in order to get my heart function back to normal. But that's not a problem anymore as Gleevec offers so many more benefits. First of all I am still alive due to this medication. And I have been in remission for seven years, isn't it an evidence of the highest quality of the drug! I know that many people complain of nasty side effects and it's natural as we are all individuals and there can be no single solution equally good for all of us. So for some people Gleevec is the best solution, others have to continue their search. But when it comes to cancer, the most important thing is not to hang your head and continue searching. Cause there is a solution, you just have to find it. God bless us all!

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I am taking Gleevec after surgery, to remove 15ccmm tumor. It has been 7 months and I am tumor free. The main side effects of taking Gleevec has been abdominal bloating with pain, at times severe. I am able to handle the side effects for the most part, but when it becomes too much, I just reduce my dose for a few days until I feel better, normally or for two days a week. I was on Gleevec for 5 months prior to surgery. It didn't reduce the tumor, but it stop its growth and reduced the density considerably.

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Sorafenib is another similar targeted therapy but it blocks more mutations, including those that develop in GIST tumors that become resistant to imatinib and sunitinib.

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Chickens, cats, and mice appear particularly susceptible, although our awareness of virus-related cancer in these animals might be mainly due to the fact that these are the ones people come across through agriculture, pets, and laboratory research.

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Due to the structural similarities of imatinib and bafetinib, their binding to Bcr-Abl is also quite similar.

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Imatinib, a tyrosine kinase inhibitor that targets the so-called Philadelphia chromosome characteristic of chronic myeloid leukemia, was the first to yield complete and lasting responses and is now widely used as first-line treatment, the researchers noted.

One other concern when using this drug to treat large GISTs is that these tumors often have a lot of fragile blood vessels.

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Most news item contrasted the huge price difference between patented Gleevec of Novartis and the generic versions of Cipla and other generic companies.

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