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Where a recent of adequate quality was found, we searched for more recent RCTs relevant to the review.

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MEM had more significant effects on cognitive function scores in the moderate-to-severe AD subgroup, but not in the mild-to-moderate AD subgroup, than was apparent in the main meta-analysis result.

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Autopsy results have shown that as many at 80% of persons with AD also have cardiovascular disease.

Laboratory Changes: Namenda and placebo groups were compared with respect to (1) mean change from baseline in various serum chemistry, hematology, and urinalysis variables and (2) the incidence of patients meeting criteria for potentially clinically significant changes from baseline in these variables.

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In the current substudy of the memantine trial, we utilized event-related brain potentials (ERPs) to detect treatment effects on neural processing, and to test if ERPs might be more sensitive to treatment effects than conventional behavioral and clinical measures used in the randomized clinical trial.

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Por un lado, los efectos secundarios cardiovasculares se vean en dosis mucho ms altas que las recetadas normalmente y por periodos de tiempo ms largos, agreg.

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Memantine is classified as an uncompetitive low-to-moderate affinity N-methyl-D-aspartate (NMDA) receptor antagonist, the first Alzheimer drug of this type approved in the United States.

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Figure 3 shows the time course for the change from baseline in SIB score for the two treatment groups over the 28 weeks of the study.

The National Institute for Health and Clinical Excellence (NICE) invites 'consultee' and 'commentator' organisations to take part in the appraisal process.

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There are two ways to recertify: 1 is to successfully complete the NCTRC exam again; and 2 is to obtain 50 hours of Continuing Education Units CEUs.

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